Inertial effect of cell state velocity on the quiescence-proliferation fate decision in breast cancer

Energy landscapes can provide intuitive depictions of population heterogeneity and dynamics. However, it is unclear whether individual cell behavior, hypothesized to be determined by initial position and noise, is faithfully recapitulated. Using the p21-/Cdk2-dependent quiescence-proliferation decis...

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Detalles Bibliográficos
Autores principales: Venkatachalapathy, Harish, Brzakala, Cole, Batchelor, Eric, Azarin, Samira M., Sarkar, Casim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245870/
https://www.ncbi.nlm.nih.gov/pubmed/37292599
http://dx.doi.org/10.1101/2023.05.22.541793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245870/
https://www.ncbi.nlm.nih.gov/pubmed/37292599
http://dx.doi.org/10.1101/2023.05.22.541793

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