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Inertial effect of cell state velocity on the quiescence-proliferation fate decision in breast cancer
Energy landscapes can provide intuitive depictions of population heterogeneity and dynamics. However, it is unclear whether individual cell behavior, hypothesized to be determined by initial position and noise, is faithfully recapitulated. Using the p21-/Cdk2-dependent quiescence-proliferation decis...
Autores principales: | Venkatachalapathy, Harish, Brzakala, Cole, Batchelor, Eric, Azarin, Samira M., Sarkar, Casim A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245870/ https://www.ncbi.nlm.nih.gov/pubmed/37292599 http://dx.doi.org/10.1101/2023.05.22.541793 |
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