Increased bleeding and thrombosis in myeloproliferative neoplasms mediated through altered expression of inherited platelet disorder genes

An altered thrombo-hemorrhagic profile has long been observed in patients with myeloproliferative neoplasms (MPNs). We hypothesized that this observed clinical phenotype may result from altered expression of genes known to harbor genetic variants in bleeding, thrombotic, or platelet disorders. Here,...

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Detalles Bibliográficos
Autores principales: Mitchell, Alan, Frontini, Mattia, Islam, Serajul, Sivapalaratnam, Suthesh, Krishnan, Anandi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245891/
https://www.ncbi.nlm.nih.gov/pubmed/37292725
http://dx.doi.org/10.1101/2023.05.23.541977

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