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Cell type-specific cis-regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cells

Although gene expression divergence has long been postulated to be the primary driver of human evolution, identifying the genes and genetic variants underlying uniquely human traits has proven to be quite challenging. Theory suggests that cell type-specific cis-regulatory variants may fuel evolution...

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Detalles Bibliográficos
Autores principales: Wang, Ban, Starr, Alexander L., Fraser, Hunter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245923/
https://www.ncbi.nlm.nih.gov/pubmed/37292820
http://dx.doi.org/10.1101/2023.05.22.541747

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