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A Conserved Core Region of the Scaffold NEMO is Essential for Signal-induced Conformational Change and Liquid-liquid Phase Separation
Scaffold proteins help mediate interactions between protein partners, often to optimize intracellular signaling. Herein, we use comparative, biochemical, biophysical, molecular, and cellular approaches to investigate how the scaffold protein NEMO contributes to signaling in the NF-κB pathway. Compar...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245932/ https://www.ncbi.nlm.nih.gov/pubmed/37292615 http://dx.doi.org/10.1101/2023.05.25.542299 |
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por DiRusso, Christopher J., DeMaria, Anthony M., Wong, Judy, Wang, Wei, Jordanides, Jack J., Whitty, Adrian, Allen, Karen N., Gilmore, Thomas D.
Publicado 2023
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Publicado 2023
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Online
Artículo
Texto