Endogenous pathology in tauopathy mice progresses via brain networks

Neurodegenerative tauopathies are hypothesized to propagate via brain networks. This is uncertain because we have lacked precise network resolution of pathology. We therefore developed whole-brain staining methods with anti-p-tau nanobodies and imaged in 3D PS19 tauopathy mice, which have pan-neuron...

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Detalles Bibliográficos
Autores principales: Ramirez, Denise M.O., Whitesell, Jennifer D., Bhagwat, Nikhil, Thomas, Talitha L., Ajay, Apoorva D., Nawaby, Ariana, Delatour, Benoît, Bay, Sylvie, LaFaye, Pierre, Knox, Joseph E., Harris, Julie A., Meeks, Julian P., Diamond, Marc I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245958/
https://www.ncbi.nlm.nih.gov/pubmed/37293074
http://dx.doi.org/10.1101/2023.05.23.541792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245958/
https://www.ncbi.nlm.nih.gov/pubmed/37293074
http://dx.doi.org/10.1101/2023.05.23.541792

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