Cargando…

Respiratory Fungal Communities are Associated with Systemic Inflammation and Predict Survival in Patients with Acute Respiratory Failure

RATIONALE: Disruption of respiratory bacterial communities predicts poor clinical outcomes in critical illness; however, the role of respiratory fungal communities (mycobiome) is poorly understood. OBJECTIVES: We investigated whether mycobiota variation in the respiratory tract is associated with ho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Britton, Noel, Yang, Haopu, Fitch, Adam, Li, Kelvin, Seyed, Khaled, Guo, Rui, Qin, Shulin, Zhang, Yingze, Bain, William, Shah, Faraaz, Biswas, Partha, Choi, Wonseok, Finkelman, Malcolm, Zhang, Yonglong, Haggerty, Catherine L., Benos, Panayiotis V., Brooks, Maria M., McVerry, Bryan J., Methe, Barbara, Kitsios, Georgios D., Morris, Alison
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246035/ https://www.ncbi.nlm.nih.gov/pubmed/37292915 http://dx.doi.org/10.1101/2023.05.11.23289861

Ejemplares similares

The upper and lower respiratory tract microbiome in severe aspiration pneumonia
por: Kitsios, Georgios D., et al.
Publicado: (2023)

Plasma 1,3-β-d-glucan levels predict adverse clinical outcomes in critical illness
por: Kitsios, Georgios D., et al.
Publicado: (2021)

Respiratory Microbiome Profiling for Etiologic Diagnosis of Pneumonia in Mechanically Ventilated Patients
por: Kitsios, Georgios D., et al.
Publicado: (2018)

Prognostic Insights from Longitudinal Multicompartment Study of Host-Microbiota Interactions in Critically Ill Patients
por: Kitsios, Georgios D., et al.
Publicado: (2023)

Prognostic Insights from Longitudinal Multicompartment Study of Host-Microbiota Interactions in Critically Ill Patients
por: Kitsios, Georgios D., et al.
Publicado: (2023)

Distinct profiles of host responses between plasma and lower respiratory tract during acute respiratory failure
por: Kitsios, Georgios D., et al.
Publicado: (2023)

Biomarker-Based Classification of Patients With Acute Respiratory Failure Into Inflammatory Subphenotypes: A Single-Center Exploratory Study
por: Drohan, Callie M., et al.
Publicado: (2021)

Protecting the lungs but hurting the kidneys: causal inference study for the risk of ventilation-induced kidney injury in ARDS
por: Yang, Haopu, et al.
Publicado: (2020)

Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome
por: Suber, Tomeka L., et al.
Publicado: (2023)

Plasma SARS-CoV-2 RNA levels as a biomarker of lower respiratory tract SARS-CoV-2 infection in critically ill patients with COVID-19
por: Jacobs, Jana L., et al.
Publicado: (2022)

COVID-19 versus Non–COVID-19 Acute Respiratory Distress Syndrome: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes
por: Bain, William, et al.
Publicado: (2021)

Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity study
por: Yang, Libing, et al.
Publicado: (2019)

Rectal Swabs from Critically Ill Patients Provide Discordant Representations of the Gut Microbiome Compared to Stool Samples
por: Fair, Katherine, et al.
Publicado: (2019)

Trajectories of host-response biomarkers and inflammatory subphenotypes in COVID-19 patients across the spectrum of respiratory support
por: Lu, Michael, et al.
Publicado: (2022)

Magnetic-activated cell sorting identifies a unique lung microbiome community
por: Dunlap, Daniel G., et al.
Publicado: (2023)

Lower Respiratory Tract Myeloid Cells Harbor SARS-Cov-2 and Display an Inflammatory Phenotype
por: Bain, William G., et al.
Publicado: (2021)

Association of the systemic host immune response with acute hyperglycemia in mechanically ventilated septic patients
por: Farooq, Nauman, et al.
Publicado: (2021)

Noninvasive diagnosis of secondary infections in COVID-19 by sequencing of plasma microbial cell-free DNA
por: Lisius, Grace, et al.
Publicado: (2023)

No evidence of hemoglobin damage by SARS-CoV-2 infection
por: DeMartino, Anthony W., et al.
Publicado: (2020)

245. Plasma and Respiratory Specimen Metagenomic Sequencing for the Diagnosis of Severe Pneumonia in Mechanically-Ventilated Patients
por: Kitsios, Georgios, et al.
Publicado: (2019)

Plasma microbial cell-free DNA load is associated with mortality in patients with COVID-19
por: Kitsios, Georgios D., et al.
Publicado: (2021)

A Pilot Double-Blind Placebo-Controlled Randomized Clinical Trial to Investigate the Effects of Early Enteral Nutrients in Sepsis
por: Shah, Faraaz Ali, et al.
Publicado: (2021)

Improved Detection of Culprit Pathogens by Bacterial DNA Sequencing Affects Antibiotic Management Decisions in Severe Pneumonia
por: Dunlap, Daniel G., et al.
Publicado: (2018)

Physiologic Effects of Exogenous Dextrose in Murine Klebsiella pneumoniae Sepsis Vary by Route of Provision
por: Chuan, Byron, et al.
Publicado: (2020)

Reply: Understanding COVID-19 Acute Respiratory Distress Syndrome: New Pathogen, Same Heterogeneous Syndrome
por: Drohan, Callie, et al.
Publicado: (2022)

Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia
por: Lai, Yandong, et al.
Publicado: (2021)

Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis
por: Lai, Yandong, et al.
Publicado: (2023)

Bifurcated monocyte states are predictive of mortality in severe COVID-19
por: Cillo, Anthony R., et al.
Publicado: (2021)

People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden
por: Cillo, Anthony R., et al.
Publicado: (2021)

Comparison of three cisatracurium dosing strategies in acute respiratory distress syndrome: A focus on drug utilization and improvement in oxygenation
por: DiBridge, Julie N., et al.
Publicado: (2021)

A common single nucleotide polymorphism is associated with inflammation and critical illness outcomes
por: El-Dehaibi, Fayten, et al.
Publicado: (2023)

Factor H preserves alternative complement function during ARDS, linked to improved survival
por: Bain, William, et al.
Publicado: (2023)

Nocturnal Hypoxia Improves Glucose Disposal, Decreases Mitochondrial Efficiency, and Increases Reactive Oxygen Species in the Muscle and Liver of C57BL/6J Mice Independent of Weight Change
por: Ioja, Simona, et al.
Publicado: (2018)

Contribution of Coronavirus-Specific Immunoglobulin G Responses to Complement Overactivation in Patients with Severe Coronavirus Disease 2019( )
por: Castanha, Priscila M S, et al.
Publicado: (2022)

Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19
por: Peddireddy, Sai Preetham, et al.
Publicado: (2022)

Mode of Delivery to the Brave New (Microbial) World: A Defining Moment for the Respiratory Microbiome?
por: Kitsios, Georgios D., et al.
Publicado: (2016)

Suppressed renoprotective purines in COVID-19 patients with acute kidney injury
por: Jackson, Edwin K., et al.
Publicado: (2022)

Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut
por: Varon, Jack, et al.
Publicado: (2022)

Is Endotoxemia in Stable Hemodialysis Patients an Artefact? Limitations of the Limulus Amebocyte Lysate Assay and Role of (1→3)-β-D Glucan
por: Wong, Jonathan, et al.
Publicado: (2016)

Beta-Glucanemia after Coronary Artery Bypass Graft Surgery: A Case Report
por: Styczynski, Ashley, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_gh51hccjk31icca1smqfhdb2jq