Pathological characteristics of axons and proteome patterns in midbrain dopaminergic neurodegeneration induced by WDR45-deficiency

BACKGROUND: Although WD repeats domain 45 (WDR45) mutations have been linked to β-propeller protein-associated neurodegeneration (BPAN), the precise molecular and cellular mechanisms behind this disease remain elusive. This study aims to shed light on the effects of WDR45-deficiency on neurodegenera...

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Detalles Bibliográficos
Autores principales: Le, Weidong, Wang, Panpan, Al-Nusaif, Murad, Zhang, Jun, Yang, Huijia, Yang, Yuting, Kim, Kunhyok, Li, Song, Liu, Cong, Cai, Huaibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246098/
https://www.ncbi.nlm.nih.gov/pubmed/37292937
http://dx.doi.org/10.21203/rs.3.rs-2901370/v1

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