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Comparing chromatin contact maps at scale: methods and insights

Comparing chromatin contact maps is an essential step in quantifying how three-dimensional (3D) genome organization shapes development, evolution, and disease. However, no gold standard exists for comparing contact maps, and even simple methods often disagree. In this study, we propose novel compari...

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Detalles Bibliográficos
Autores principales: Gunsalus, Laura M., McArthur, Evonne, Gjoni, Ketrin, Kuang, Shuzhen, Pittman, Maureen, Capra, John A., Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246266/
https://www.ncbi.nlm.nih.gov/pubmed/37292728
http://dx.doi.org/10.21203/rs.3.rs-2842981/v1