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Comparing chromatin contact maps at scale: methods and insights
Comparing chromatin contact maps is an essential step in quantifying how three-dimensional (3D) genome organization shapes development, evolution, and disease. However, no gold standard exists for comparing contact maps, and even simple methods often disagree. In this study, we propose novel compari...
Autores principales: | Gunsalus, Laura M., McArthur, Evonne, Gjoni, Ketrin, Kuang, Shuzhen, Pittman, Maureen, Capra, John A., Pollard, Katherine S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246266/ https://www.ncbi.nlm.nih.gov/pubmed/37292728 http://dx.doi.org/10.21203/rs.3.rs-2842981/v1 |
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