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Malaria Transmission Intensity and Parasitemia during the Three-Dose RTS,S/AS01 Vaccination Series do not Reduce Magnitude of Antibody Response nor Efficacy Against the First Case of Malaria

BACKGROUND: RTS,S/AS01 has been recommended by WHO for widespread implementation in medium to high malaria transmission settings. Previous analyses have noted lower vaccine efficacies in higher transmission settings, possibly due to the more rapid development of naturally acquired immunity in the co...

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Detalles Bibliográficos
Autores principales: Bell, Griffin J, Gyaase, Stephaney, Goel, Varun, Adu, Bright, Mensah, Benedicta, Essone, Paulin, Dosoo, David, Osei, Musah, Niare, Karamoko, Wiru, Kenneth, Brandt, Katerina, Emch, Michael, Ghansah, Anita, Asante, Kwaku Poku, Mvalo, Tisungane, Agnandji, Selidhi Todagbe, Juliano, Jonathan J, Bailey, Jeffrey A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246269/
https://www.ncbi.nlm.nih.gov/pubmed/37292711
http://dx.doi.org/10.21203/rs.3.rs-2960373/v1