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Accumulation of m(6)A exhibits stronger correlation with MAPT than β-amyloid pathology in an APP(NL-G-F) /MAPT(P301S) mouse model of Alzheimer’s disease
The study for the pathophysiology study of Alzheimer’s disease (AD) has been hampered by lack animal models that recapitulate the major AD pathologies, including extracellular β-amyloid (Aβ) deposition, intracellular aggregation of microtubule associated protein tau (MAPT), inflammation and neurodeg...
Autores principales: | Jiang, Lulu, Roberts, Rebecca, Wong, Melissa, Zhang, Lushuang, Webber, Chelsea Joy, Kilci, Alper, Jenkins, Matthew, Sun, Jingjing, Sun, Guangxin, Rashad, Sherif, Dedon, Peter C, Daley, Sarah Anne, Xia, Weiming, Ortiz, Alejandro Rondón, Dorrian, Luke, Saito, Takashi, Saido, Takaomi C., Wolozin, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246280/ https://www.ncbi.nlm.nih.gov/pubmed/37292629 http://dx.doi.org/10.21203/rs.3.rs-2745852/v1 |
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