Accumulation of m(6)A exhibits stronger correlation with MAPT than β-amyloid pathology in an APP(NL-G-F) /MAPT(P301S) mouse model of Alzheimer’s disease

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The study for the pathophysiology study of Alzheimer’s disease (AD) has been hampered by lack animal models that recapitulate the major AD pathologies, including extracellular β-amyloid (Aβ) deposition, intracellular aggregation of microtubule associated protein tau (MAPT), inflammation and neurodeg...

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Detalles Bibliográficos
Autores principales: Jiang, Lulu, Roberts, Rebecca, Wong, Melissa, Zhang, Lushuang, Webber, Chelsea Joy, Kilci, Alper, Jenkins, Matthew, Sun, Jingjing, Sun, Guangxin, Rashad, Sherif, Dedon, Peter C, Daley, Sarah Anne, Xia, Weiming, Ortiz, Alejandro Rondón, Dorrian, Luke, Saito, Takashi, Saido, Takaomi C., Wolozin, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246280/
https://www.ncbi.nlm.nih.gov/pubmed/37292629
http://dx.doi.org/10.21203/rs.3.rs-2745852/v1
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