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Kinetic and inhibition studies on human Jumonji-C (JmjC) domain-containing protein 5

Jumonji-C (JmjC) domain-containing protein 5 (JMJD5) is a human 2-oxoglutarate (2OG) and Fe(ii)-dependent oxygenase which catalyses the post-translational C3 hydroxylation of arginyl-residues and which is linked to the circadian rhythm and to cancer biology through as yet unidentified mechanisms. We...

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Detalles Bibliográficos
Autores principales: Tumber, Anthony, Salah, Eidarus, Brewitz, Lennart, Corner, Thomas P., Schofield, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246557/
https://www.ncbi.nlm.nih.gov/pubmed/37292060
http://dx.doi.org/10.1039/d2cb00249c