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Site-specific chirality-conferred structural compaction differentially mediates the cytotoxicity of Aβ42

Growing evidence supports the confident association between distinct amyloid beta (Aβ) isoforms and Alzheimer's Disease (AD) pathogenesis. As such, critical investigations seeking to uncover the translational factors contributing to Aβ toxicity represent a venture of significant value. Herein,...

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Detalles Bibliográficos
Autores principales: Li, Gongyu, Jeon, Chae Kyung, Ma, Min, Jia, Yifei, Zheng, Zhen, Delafield, Daniel G., Lu, Gaoyuan, Romanova, Elena V., Sweedler, Jonathan V., Ruotolo, Brandon T., Li, Lingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246695/
https://www.ncbi.nlm.nih.gov/pubmed/37293657
http://dx.doi.org/10.1039/d3sc00678f

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