Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease

The incidence of Alzheimer’s disease (AD), the leading cause of dementia, increases rapidly with age, but why age constitutes the main risk factor is still poorly understood. Brain ageing affects oligodendrocytes and the structural integrity of myelin sheaths(1), the latter of which is associated wi...

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Detalles Bibliográficos
Autores principales: Depp, Constanze, Sun, Ting, Sasmita, Andrew Octavian, Spieth, Lena, Berghoff, Stefan A., Nazarenko, Taisiia, Overhoff, Katharina, Steixner-Kumar, Agnes A., Subramanian, Swati, Arinrad, Sahab, Ruhwedel, Torben, Möbius, Wiebke, Göbbels, Sandra, Saher, Gesine, Werner, Hauke B., Damkou, Alkmini, Zampar, Silvia, Wirths, Oliver, Thalmann, Maik, Simons, Mikael, Saito, Takashi, Saido, Takaomi, Krueger-Burg, Dilja, Kawaguchi, Riki, Willem, Michael, Haass, Christian, Geschwind, Daniel, Ehrenreich, Hannelore, Stassart, Ruth, Nave, Klaus-Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247380/
https://www.ncbi.nlm.nih.gov/pubmed/37258678
http://dx.doi.org/10.1038/s41586-023-06120-6

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