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Resistance to thyroid hormone induced tachycardia in RTHα syndrome

Mutations in thyroid hormone receptor α1 (TRα1) cause Resistance to Thyroid Hormone α (RTHα), a disorder characterized by hypothyroidism in TRα1-expressing tissues including the heart. Surprisingly, we report that treatment of RTHα patients with thyroxine to overcome tissue hormone resistance does n...

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Detalles Bibliográficos
Autores principales:	Dore, Riccardo, Watson, Laura, Hollidge, Stefanie, Krause, Christin, Sentis, Sarah Christine, Oelkrug, Rebecca, Geißler, Cathleen, Johann, Kornelia, Pedaran, Mehdi, Lyons, Greta, Lopez-Alcantara, Nuria, Resch, Julia, Sayk, Friedhelm, Iwen, Karl Alexander, Franke, Andre, Boysen, Teide Jens, Dalley, Jeffrey W., Lorenz, Kristina, Moran, Carla, Rennie, Kirsten L., Arner, Anders, Kirchner, Henriette, Chatterjee, Krishna, Mittag, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247713/ https://www.ncbi.nlm.nih.gov/pubmed/37286550 http://dx.doi.org/10.1038/s41467-023-38960-1

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