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Association analysis of gut microbiota-metabolites-neuroendocrine changes in male rats acute exposure to simulated altitude of 5500 m

Hyperactivation of hypothalamic–pituitary–adrenal (HPA) axis and hypothalamic–pituitary–thyroid (HPT) axis were found in acute high altitude challenge, but the role of gut microbiota and metabolites is unknown. We utilized adult male Sprague–Dawley rats at a simulated altitude of 5500 m for 3 days i...

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Detalles Bibliográficos
Autores principales: Wang, Jianan, Liu, Shiying, Xie, Yalei, Xu, Chengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247716/
https://www.ncbi.nlm.nih.gov/pubmed/37286697
http://dx.doi.org/10.1038/s41598-023-35573-y