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LDLR gene’s promoter region hypermethylation in patients with familial hypercholesterolemia

Familial hypercholesterolemia (FH) is characterized by high low-density lipoprotein cholesterol (LDL-C) levels and a high risk of early coronary heart disease. Structural alterations in the LDLR, APOB, and PCSK9 genes were not found in 20–40% of patients diagnosed using the Dutch Lipid Clinic Networ...

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Detalles Bibliográficos
Autores principales:	Zorzo, R. A., Suen, V. M. M., Santos, J. E., Silva-Jr, W. A., Suazo, V. K., Honorato, A. L. S. C., Santos, R. D., Jannes, C. E., Pereira, A., Krieger, J. E., Liberatore-Jr, R. D. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247769/ https://www.ncbi.nlm.nih.gov/pubmed/37286669 http://dx.doi.org/10.1038/s41598-023-34639-1

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