Cargando…

Combining machine learning with Cox models to identify predictors for incident post-menopausal breast cancer in the UK Biobank

We aimed to identify potential novel predictors for breast cancer among post-menopausal women, with pre-specified interest in the role of polygenic risk scores (PRS) for risk prediction. We utilised an analysis pipeline where machine learning was used for feature selection, prior to risk prediction...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiaonan, Morelli, Davide, Littlejohns, Thomas J., Clifton, David A., Clifton, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247810/
https://www.ncbi.nlm.nih.gov/pubmed/37286615
http://dx.doi.org/10.1038/s41598-023-36214-0