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Combining machine learning with Cox models to identify predictors for incident post-menopausal breast cancer in the UK Biobank
We aimed to identify potential novel predictors for breast cancer among post-menopausal women, with pre-specified interest in the role of polygenic risk scores (PRS) for risk prediction. We utilised an analysis pipeline where machine learning was used for feature selection, prior to risk prediction...
Autores principales: | Liu, Xiaonan, Morelli, Davide, Littlejohns, Thomas J., Clifton, David A., Clifton, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247810/ https://www.ncbi.nlm.nih.gov/pubmed/37286615 http://dx.doi.org/10.1038/s41598-023-36214-0 |
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