High-content high-throughput imaging reveals distinct connections between mitochondrial morphology and functionality for OXPHOS complex I, III, and V inhibitors

Cells can adjust their mitochondrial morphology by altering the balance between mitochondrial fission and fusion to adapt to stressful conditions. The connection between a chemical perturbation, changes in mitochondrial function, and altered mitochondrial morphology is not well understood. Here, we...

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Detalles Bibliográficos
Autores principales: van der Stel, Wanda, Yang, Huan, le Dévédec, Sylvia E., van de Water, Bob, Beltman, Joost B., Danen, Erik H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247858/
https://www.ncbi.nlm.nih.gov/pubmed/35505273
http://dx.doi.org/10.1007/s10565-022-09712-6

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