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The role of conduction system pacing in patients with atrial fibrillation
Conduction system pacing (CSP) has emerged as a promising novel delivery method for Cardiac Resynchronisation Therapy (CRT), providing an alternative to conventional biventricular epicardial (BiV) pacing in indicated patients. Despite increasing popularity and widespread uptake, CSP has rarely been...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248047/ https://www.ncbi.nlm.nih.gov/pubmed/37304966 http://dx.doi.org/10.3389/fcvm.2023.1187754 |
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author | Wijesuriya, Nadeev Mehta, Vishal De Vere, Felicity Strocchi, Marina Behar, Jonathan M. Niederer, Steven A. Rinaldi, Christopher A. |
author_facet | Wijesuriya, Nadeev Mehta, Vishal De Vere, Felicity Strocchi, Marina Behar, Jonathan M. Niederer, Steven A. Rinaldi, Christopher A. |
author_sort | Wijesuriya, Nadeev |
collection | PubMed |
description | Conduction system pacing (CSP) has emerged as a promising novel delivery method for Cardiac Resynchronisation Therapy (CRT), providing an alternative to conventional biventricular epicardial (BiV) pacing in indicated patients. Despite increasing popularity and widespread uptake, CSP has rarely been specifically examined in patients with atrial fibrillation (AF), a cohort which forms a significant proportion of the heart failure (HF) population. In this review, we first examine the mechanistic evidence for the importance of sinus rhythm (SR) in CSP by allowing adjustment of atrioventricular delays (AVD) to achieve the optimal electrical response, and thus, whether the efficacy of CSP may be significantly attenuated compared to conventional BiV pacing in the presence of AF. We next evaluate the largest clinical body of evidence in this field, related to patients receiving CSP following atrioventricular nodal ablation (AVNA) for AF. Finally, we discuss how future research may be designed to address the vital question of how effective CSP in AF patients is, and the potential hurdles we may face in delivering such studies. |
format | Online Article Text |
id | pubmed-10248047 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102480472023-06-09 The role of conduction system pacing in patients with atrial fibrillation Wijesuriya, Nadeev Mehta, Vishal De Vere, Felicity Strocchi, Marina Behar, Jonathan M. Niederer, Steven A. Rinaldi, Christopher A. Front Cardiovasc Med Cardiovascular Medicine Conduction system pacing (CSP) has emerged as a promising novel delivery method for Cardiac Resynchronisation Therapy (CRT), providing an alternative to conventional biventricular epicardial (BiV) pacing in indicated patients. Despite increasing popularity and widespread uptake, CSP has rarely been specifically examined in patients with atrial fibrillation (AF), a cohort which forms a significant proportion of the heart failure (HF) population. In this review, we first examine the mechanistic evidence for the importance of sinus rhythm (SR) in CSP by allowing adjustment of atrioventricular delays (AVD) to achieve the optimal electrical response, and thus, whether the efficacy of CSP may be significantly attenuated compared to conventional BiV pacing in the presence of AF. We next evaluate the largest clinical body of evidence in this field, related to patients receiving CSP following atrioventricular nodal ablation (AVNA) for AF. Finally, we discuss how future research may be designed to address the vital question of how effective CSP in AF patients is, and the potential hurdles we may face in delivering such studies. Frontiers Media S.A. 2023-05-25 /pmc/articles/PMC10248047/ /pubmed/37304966 http://dx.doi.org/10.3389/fcvm.2023.1187754 Text en © 2023 Wijesuriya, Mehta, De Vere, Strocchi, Behar, Niederer and Rinaldi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cardiovascular Medicine Wijesuriya, Nadeev Mehta, Vishal De Vere, Felicity Strocchi, Marina Behar, Jonathan M. Niederer, Steven A. Rinaldi, Christopher A. The role of conduction system pacing in patients with atrial fibrillation |
title | The role of conduction system pacing in patients with atrial fibrillation |
title_full | The role of conduction system pacing in patients with atrial fibrillation |
title_fullStr | The role of conduction system pacing in patients with atrial fibrillation |
title_full_unstemmed | The role of conduction system pacing in patients with atrial fibrillation |
title_short | The role of conduction system pacing in patients with atrial fibrillation |
title_sort | role of conduction system pacing in patients with atrial fibrillation |
topic | Cardiovascular Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248047/ https://www.ncbi.nlm.nih.gov/pubmed/37304966 http://dx.doi.org/10.3389/fcvm.2023.1187754 |
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