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Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma

INTRODUCTION: Chimeric antigen receptor T (CAR-T) cell therapy presents a promising treatment option for various cancers, including solid tumors. Carcinoembryonic antigen (CEA) is an attractive target due to its high expression in many tumors, particularly gastrointestinal cancers, while limited exp...

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Detalles Bibliográficos
Autores principales: Zhang, Chengcheng, Wang, Linling, Zhang, Qianzhen, Shen, Junjie, Huang, Xia, Wang, Meiling, Huang, Yi, Chen, Jun, Xu, Yanmin, Zhao, Wenxu, Qi, Yanan, Li, Yunyan, Ou, Yanjiao, Yang, Zhi, Qian, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248079/
https://www.ncbi.nlm.nih.gov/pubmed/37304295
http://dx.doi.org/10.3389/fimmu.2023.1182409

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