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Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma
INTRODUCTION: Chimeric antigen receptor T (CAR-T) cell therapy presents a promising treatment option for various cancers, including solid tumors. Carcinoembryonic antigen (CEA) is an attractive target due to its high expression in many tumors, particularly gastrointestinal cancers, while limited exp...
Autores principales: | Zhang, Chengcheng, Wang, Linling, Zhang, Qianzhen, Shen, Junjie, Huang, Xia, Wang, Meiling, Huang, Yi, Chen, Jun, Xu, Yanmin, Zhao, Wenxu, Qi, Yanan, Li, Yunyan, Ou, Yanjiao, Yang, Zhi, Qian, Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248079/ https://www.ncbi.nlm.nih.gov/pubmed/37304295 http://dx.doi.org/10.3389/fimmu.2023.1182409 |
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