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Bone marrow metastasis of testicular germ cell tumour: A rare case
Germ cell tumour (GCT) is the most common testicular tumour that commonly presents as a painless mass. Bone marrow metastasis in cases of testicular GCT is rare; only few case reports are available till date in the literature. Here an adult male presented with an intra-abdominal mass in right iliac...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248114/ https://www.ncbi.nlm.nih.gov/pubmed/37303538 http://dx.doi.org/10.1016/j.heliyon.2023.e16703 |
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author | Dubey, Harshita Jain, Garima Kumar, Chandan Ranjan, Amar Batra, Atul Chellapuram, Santosh Kumar Gupta, Swati Goel, Harsh Sharma, Anil Tanwar, Pranay |
author_facet | Dubey, Harshita Jain, Garima Kumar, Chandan Ranjan, Amar Batra, Atul Chellapuram, Santosh Kumar Gupta, Swati Goel, Harsh Sharma, Anil Tanwar, Pranay |
author_sort | Dubey, Harshita |
collection | PubMed |
description | Germ cell tumour (GCT) is the most common testicular tumour that commonly presents as a painless mass. Bone marrow metastasis in cases of testicular GCT is rare; only few case reports are available till date in the literature. Here an adult male presented with an intra-abdominal mass in right iliac fossa with inguinal lymphadenopathy with a deranged kidney function test. Bone marrow (BM) aspirate smear revealed metastatic tumour cells, but BM-biopsy was unremarkable. High serum Beta - HCG (38286 mIU/L) pointed towards germ cell lesion. Lymph node biopsy along with immunomarkers confirmed metastatic foci from germ cell tumor and managed as per standard protocol. Rarely BM aspirate is seen positive for malignancy, while biopsy turns out to be negative. Secondly, BM metastasis of GCT should be considered while dealing with cases like this. INFORMED CONSENT: This is certified that the informed consent has been obtained from the patient. |
format | Online Article Text |
id | pubmed-10248114 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-102481142023-06-09 Bone marrow metastasis of testicular germ cell tumour: A rare case Dubey, Harshita Jain, Garima Kumar, Chandan Ranjan, Amar Batra, Atul Chellapuram, Santosh Kumar Gupta, Swati Goel, Harsh Sharma, Anil Tanwar, Pranay Heliyon Case Report Germ cell tumour (GCT) is the most common testicular tumour that commonly presents as a painless mass. Bone marrow metastasis in cases of testicular GCT is rare; only few case reports are available till date in the literature. Here an adult male presented with an intra-abdominal mass in right iliac fossa with inguinal lymphadenopathy with a deranged kidney function test. Bone marrow (BM) aspirate smear revealed metastatic tumour cells, but BM-biopsy was unremarkable. High serum Beta - HCG (38286 mIU/L) pointed towards germ cell lesion. Lymph node biopsy along with immunomarkers confirmed metastatic foci from germ cell tumor and managed as per standard protocol. Rarely BM aspirate is seen positive for malignancy, while biopsy turns out to be negative. Secondly, BM metastasis of GCT should be considered while dealing with cases like this. INFORMED CONSENT: This is certified that the informed consent has been obtained from the patient. Elsevier 2023-05-29 /pmc/articles/PMC10248114/ /pubmed/37303538 http://dx.doi.org/10.1016/j.heliyon.2023.e16703 Text en © 2023 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Dubey, Harshita Jain, Garima Kumar, Chandan Ranjan, Amar Batra, Atul Chellapuram, Santosh Kumar Gupta, Swati Goel, Harsh Sharma, Anil Tanwar, Pranay Bone marrow metastasis of testicular germ cell tumour: A rare case |
title | Bone marrow metastasis of testicular germ cell tumour: A rare case |
title_full | Bone marrow metastasis of testicular germ cell tumour: A rare case |
title_fullStr | Bone marrow metastasis of testicular germ cell tumour: A rare case |
title_full_unstemmed | Bone marrow metastasis of testicular germ cell tumour: A rare case |
title_short | Bone marrow metastasis of testicular germ cell tumour: A rare case |
title_sort | bone marrow metastasis of testicular germ cell tumour: a rare case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248114/ https://www.ncbi.nlm.nih.gov/pubmed/37303538 http://dx.doi.org/10.1016/j.heliyon.2023.e16703 |
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