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Evolutionary analysis and structure modelling of the Rcs-repressor IgaA unveil a functional role of two cytoplasmic small β-barrel (SBB) domains

The Rcs sensor system, comprising the RcsB/RcsC/RcsD and RcsF proteins, is used by bacteria of the order Enterobacterales to withstand envelope damage. In non-stress conditions, Rcs is repressed by IgaA, a membrane protein with three cytoplasmic regions (cyt-1, cyt-2 and cyt-3). How the Rcs-IgaA axi...

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Detalles Bibliográficos
Autores principales: Rodríguez, Leticia, Peñalver, Marcos, Casino, Patricia, García-del Portillo, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248123/
https://www.ncbi.nlm.nih.gov/pubmed/37303533
http://dx.doi.org/10.1016/j.heliyon.2023.e16661

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