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Targeting the autophagy-lysosomal pathway in Huntington disease: a pharmacological perspective
The autophagy-lysosomal pathway (ALP) is the major biological pathway responsible for clearing intracellular protein aggregates, therefore a promising target for treating diseases featuring the accumulation of aggregation-prone proteins, such as Huntington disease (HD). However, accumulating evidenc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248240/ https://www.ncbi.nlm.nih.gov/pubmed/37304076 http://dx.doi.org/10.3389/fnagi.2023.1175598 |