Cargando…

Allosteric modulation of gonadotropin receptors

Gonadotropins regulate reproductive functions by binding to G protein-coupled receptors (FSHR and LHCGR) expressed in the gonads. They activate multiple, cell-specific signalling pathways, consisting of ligand-dependent intracellular events. Signalling cascades may be modulated by synthetic compound...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lazzaretti, Clara, Simoni, Manuela, Casarini, Livio, Paradiso, Elia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248450/ https://www.ncbi.nlm.nih.gov/pubmed/37305033 http://dx.doi.org/10.3389/fendo.2023.1179079

Ejemplares similares

Endocrine Disruption of the Follicle-Stimulating Hormone Receptor Signaling During the Human Antral Follicle Growth
por: Roy, Neena, et al.
Publicado: (2021)

Identification of Key Receptor Residues Discriminating Human Chorionic Gonadotropin (hCG)- and Luteinizing Hormone (LH)-Specific Signaling
por: Lazzaretti, Clara, et al.
Publicado: (2020)

Efficacy of Follicle-Stimulating Hormone (FSH) Alone, FSH + Luteinizing Hormone, Human Menopausal Gonadotropin or FSH + Human Chorionic Gonadotropin on Assisted Reproductive Technology Outcomes in the “Personalized” Medicine Era: A Meta-analysis
por: Santi, Daniele, et al.
Publicado: (2017)

Response: Commentary: Efficacy of Follicle-Stimulating Hormone (FSH) Alone, FSH + Luteinizing Hormone, Human Menopausal Gonadotropin or FSH + Human Chorionic Gonadotropin on Assisted Reproductive Technology Outcomes in the “Personalized” Medicine Era: A Meta-analysis
por: Santi, Daniele, et al.
Publicado: (2018)

Recent advances in understanding gonadotropin signaling
por: Casarini, Livio, et al.
Publicado: (2021)

FSH for the Treatment of Male Infertility
por: Casarini, Livio, et al.
Publicado: (2020)

The “Hitchhiker’s Guide to the Galaxy” of Endothelial Dysfunction Markers in Human Fertility
por: Santi, Daniele, et al.
Publicado: (2021)

Intracellular cGMP increase is not involved in thyroid cancer cell death
por: Alessandro, Sara D’, et al.
Publicado: (2023)

Glycosylation Pattern and in vitro Bioactivity of Reference Follitropin alfa and Biosimilars
por: Riccetti, Laura, et al.
Publicado: (2019)

GnRH Antagonists Produce Differential Modulation of the Signaling Pathways Mediated by GnRH Receptors
por: Sperduti, Samantha, et al.
Publicado: (2019)

Editorial: Follicle-Stimulating Hormone: Fertility and Beyond
por: Simoni, Manuela, et al.
Publicado: (2019)

Editorial: Follicle-stimulating hormone: Fertility and beyond-volume II
por: Simoni, Manuela, et al.
Publicado: (2022)

MON-486 Polygenic Susceptibility to Papillary Thyroid Cancer in Italian Subjects
por: Brigante, Giulia, et al.
Publicado: (2020)

Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors
por: Riccetti, Laura, et al.
Publicado: (2017)

Effect of Genetic Variants of Gonadotropins and Their Receptors on Ovarian Stimulation Outcomes: A Delphi Consensus
por: Conforti, Alessandro, et al.
Publicado: (2022)

Allosteric modulation of G protein-coupled receptor signaling
por: Shen, Siyuan, et al.
Publicado: (2023)

Drug Repositioning For Allosteric Modulation of VIP and PACAP Receptors
por: Langer, Ingrid, et al.
Publicado: (2021)

Modulation of Gonadotropins Activity by Antibodies
por: Kara, Elodie, et al.
Publicado: (2019)

Small molecule allosteric modulation of the adenosine A(1) receptor
por: Nguyen, Anh T. N., et al.
Publicado: (2023)

Discovery and Development of Small Molecule Allosteric Modulators of Glycoprotein Hormone Receptors
por: Nataraja, Selvaraj G., et al.
Publicado: (2015)

Biased Signaling and Allosteric Modulation at the FSHR
por: Landomiel, Flavie, et al.
Publicado: (2019)

OR24-04 Ovarian Follicle Survival Is Determined by Follicle-Stimulating Hormone Receptor (FSHR) and Estrogen Receptor (GPER) Heteromers
por: Casarini, Livio, et al.
Publicado: (2020)

Seasonal Changes of Serum Gonadotropins and Testosterone in Men Revealed by a Large Data Set of Real-World Observations Over Nine Years
por: Santi, Daniele, et al.
Publicado: (2020)

Molecular Mechanisms of Action of FSH
por: Casarini, Livio, et al.
Publicado: (2019)

Editorial: Gonadotropin-Releasing Hormone Receptor Signaling and Functions
por: Bjelobaba, Ivana, et al.
Publicado: (2018)

Invertebrate Gonadotropin-Releasing Hormone-Related Peptides and Their Receptors: An Update
por: Sakai, Tsubasa, et al.
Publicado: (2017)

β-arrestin 2 Is a Prognostic Factor for Survival of Ovarian Cancer Patients Upregulating Cell Proliferation
por: Czogalla, Bastian, et al.
Publicado: (2020)

Short-Term Exposure to Bisphenol A Does Not Impact Gonadal Cell Steroidogenesis In Vitro
por: Roy, Neena, et al.
Publicado: (2023)

Genetic signature of differentiated thyroid carcinoma susceptibility: a machine learning approach
por: Brigante, Giulia, et al.
Publicado: (2022)

Assessing Gonadotropin Receptor Function by Resonance Energy Transfer-Based Assays
por: Ayoub, Mohammed Akli, et al.
Publicado: (2015)

Expression and Role of Gonadotropin-Releasing Hormone 2 and Its Receptor in Mammals
por: Desaulniers, Amy T., et al.
Publicado: (2017)

Central and Direct Regulation of Testicular Activity by Gonadotropin-Inhibitory Hormone and Its Receptor
por: Ubuka, Takayoshi, et al.
Publicado: (2014)

Gonadotropin-Releasing Hormone (GnRH) Receptor Structure and GnRH Binding
por: Flanagan, Colleen A., et al.
Publicado: (2017)

Gonadotropins at Advanced Age - Perhaps They Are Not So Bad? Correlations Between Gonadotropins and Sarcopenia Indicators in Older Adults
por: Guligowska, Agnieszka, et al.
Publicado: (2021)

Reactive Oxygen Species Link Gonadotropin-Releasing Hormone Receptor Signaling Cascades in the Gonadotrope
por: Terasaka, Tomohiro, et al.
Publicado: (2017)

Intrinsic and Regulated Gonadotropin-Releasing Hormone Receptor Gene Transcription in Mammalian Pituitary Gonadotrophs
por: Janjic, Marija M., et al.
Publicado: (2017)

Gonadotropin Inhibitory Hormone and Its Receptor: Potential Key to the Integration and Coordination of Metabolic Status and Reproduction
por: Bédécarrats, Grégoy Y., et al.
Publicado: (2022)

Modulation of Gonadotropin-Releasing Hormone Neuron Activity and Secretion in Mice by Non-peptide Neurotransmitters, Gasotransmitters, and Gliotransmitters
por: Spergel, Daniel J.
Publicado: (2019)

Membrane Estrogen Receptor (GPER) and Follicle-Stimulating Hormone Receptor (FSHR) Heteromeric Complexes Promote Human Ovarian Follicle Survival
por: Casarini, Livio, et al.
Publicado: (2020)

Regulation of gonadotropins by corticotropin-releasing factor and urocortin
por: Kageyama, Kazunori
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ah2g76a1o7o5vvbjjce4h993bn