Pharmacological inhibition of DNMT1 restores macrophage autophagy and M2 polarization in Western diet–induced nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is associated with an increased ratio of classically activated M1 macrophages/Kupffer cells to alternatively activated M2 macrophages, which plays an imperative role in the development and progression of NAFLD. However, little is known about the precise mecha...

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Detalles Bibliográficos
Autores principales: Pant, Rajat, Kabeer, Shaheen Wasil, Sharma, Shivam, Kumar, Vinod, Patra, Debarun, Pal, Durba, Tikoo, Kulbhushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248527/
https://www.ncbi.nlm.nih.gov/pubmed/37142224
http://dx.doi.org/10.1016/j.jbc.2023.104779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248527/
https://www.ncbi.nlm.nih.gov/pubmed/37142224
http://dx.doi.org/10.1016/j.jbc.2023.104779

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