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Pharmacological inhibition of DNMT1 restores macrophage autophagy and M2 polarization in Western diet–induced nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is associated with an increased ratio of classically activated M1 macrophages/Kupffer cells to alternatively activated M2 macrophages, which plays an imperative role in the development and progression of NAFLD. However, little is known about the precise mecha...
Autores principales: | Pant, Rajat, Kabeer, Shaheen Wasil, Sharma, Shivam, Kumar, Vinod, Patra, Debarun, Pal, Durba, Tikoo, Kulbhushan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248527/ https://www.ncbi.nlm.nih.gov/pubmed/37142224 http://dx.doi.org/10.1016/j.jbc.2023.104779 |
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