Solubilization, purification, and characterization of the hexameric form of phosphatidylserine synthase from Candida albicans

Phosphatidylserine (PS) synthase from Candida albicans, encoded by the CHO1 gene, has been identified as a potential drug target for new antifungals against systemic candidiasis. Rational drug design or small molecule screening are effective ways to identify specific inhibitors of Cho1, but both wil...

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Detalles Bibliográficos
Autores principales: Zhou, Yue, Syed, Jawhar H., Semchonok, Dmitry A., Wright, Edward, Kyrilis, Fotis L., Hamdi, Farzad, Kastritis, Panagiotis L., Bruce, Barry D., Reynolds, Todd B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248529/
https://www.ncbi.nlm.nih.gov/pubmed/37116705
http://dx.doi.org/10.1016/j.jbc.2023.104756

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