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The ribosomal S6 kinase 2 (RSK2)–SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling

Sprouty-related EVH-1 domain-containing (SPRED) proteins are a family of proteins that negatively regulate the RAS-Mitogen-Activated Protein Kinase (MAPK) pathway, which is involved in the regulation of the mitogenic response and cell proliferation. However, the mechanism by which these proteins aff...

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Detalles Bibliográficos
Autores principales: Lopez, Jocelyne, Bonsor, Daniel A., Sale, Matthew J., Urisman, Anatoly, Mehalko, Jennifer L., Cabanski-Dunning, Miranda, Castel, Pau, Simanshu, Dhirendra K., McCormick, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248553/
https://www.ncbi.nlm.nih.gov/pubmed/37149146
http://dx.doi.org/10.1016/j.jbc.2023.104789

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