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The ribosomal S6 kinase 2 (RSK2)–SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling
Sprouty-related EVH-1 domain-containing (SPRED) proteins are a family of proteins that negatively regulate the RAS-Mitogen-Activated Protein Kinase (MAPK) pathway, which is involved in the regulation of the mitogenic response and cell proliferation. However, the mechanism by which these proteins aff...
Autores principales: | Lopez, Jocelyne, Bonsor, Daniel A., Sale, Matthew J., Urisman, Anatoly, Mehalko, Jennifer L., Cabanski-Dunning, Miranda, Castel, Pau, Simanshu, Dhirendra K., McCormick, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248553/ https://www.ncbi.nlm.nih.gov/pubmed/37149146 http://dx.doi.org/10.1016/j.jbc.2023.104789 |
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