Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation

[Image: see text] Core–shell quantum dot ZnS/CdSe screen-printed electrodes were used to electrochemically measure human blood plasma levels of exogenous adrenaline administered to cardiac arrest patients. The electrochemical behavior of adrenaline on the modified electrode surface was investigated...

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Autores principales: Altuntaş, Mehmet, Altuntaş, Derya Bal, Aslan, Sema, Yılmaz, Ersin, Nalbant, Ercan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249028/
https://www.ncbi.nlm.nih.gov/pubmed/37305245
http://dx.doi.org/10.1021/acsomega.3c00555
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author Altuntaş, Mehmet
Altuntaş, Derya Bal
Aslan, Sema
Yılmaz, Ersin
Nalbant, Ercan
author_facet Altuntaş, Mehmet
Altuntaş, Derya Bal
Aslan, Sema
Yılmaz, Ersin
Nalbant, Ercan
author_sort Altuntaş, Mehmet
collection PubMed
description [Image: see text] Core–shell quantum dot ZnS/CdSe screen-printed electrodes were used to electrochemically measure human blood plasma levels of exogenous adrenaline administered to cardiac arrest patients. The electrochemical behavior of adrenaline on the modified electrode surface was investigated using differential pulse voltammetry (DPV), cyclic voltammetry, and electrochemical impedance spectroscopy (EIS). Under optimal conditions, the linear working ranges of the modified electrode were 0.001–3 μM (DPV) and 0.001–300 μM (EIS). The best limit of detection for this concentration range was 2.79 × 10(–8) μM (DPV). The modified electrodes showed good reproducibility, stability, and sensitivity and successfully detected adrenaline levels.
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spelling pubmed-102490282023-06-09 Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation Altuntaş, Mehmet Altuntaş, Derya Bal Aslan, Sema Yılmaz, Ersin Nalbant, Ercan ACS Omega [Image: see text] Core–shell quantum dot ZnS/CdSe screen-printed electrodes were used to electrochemically measure human blood plasma levels of exogenous adrenaline administered to cardiac arrest patients. The electrochemical behavior of adrenaline on the modified electrode surface was investigated using differential pulse voltammetry (DPV), cyclic voltammetry, and electrochemical impedance spectroscopy (EIS). Under optimal conditions, the linear working ranges of the modified electrode were 0.001–3 μM (DPV) and 0.001–300 μM (EIS). The best limit of detection for this concentration range was 2.79 × 10(–8) μM (DPV). The modified electrodes showed good reproducibility, stability, and sensitivity and successfully detected adrenaline levels. American Chemical Society 2023-05-25 /pmc/articles/PMC10249028/ /pubmed/37305245 http://dx.doi.org/10.1021/acsomega.3c00555 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Altuntaş, Mehmet
Altuntaş, Derya Bal
Aslan, Sema
Yılmaz, Ersin
Nalbant, Ercan
Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation
title Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation
title_full Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation
title_fullStr Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation
title_full_unstemmed Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation
title_short Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation
title_sort determination of exogenous adrenaline levels in patients undergoing cardiopulmonary resuscitation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249028/
https://www.ncbi.nlm.nih.gov/pubmed/37305245
http://dx.doi.org/10.1021/acsomega.3c00555
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