5-Nitro-1,2-benzothiazol-3-amine and N-Ethyl-1-[(ethylcarbamoyl)(5-nitro-1,2-benzothiazol-3-yl)amino]formamide Modulate α-Synuclein and Tau Aggregation

[Image: see text] Protein misfolding results in a plethora of known diseases such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, transthyretin-related amyloidosis, type 2 diabetes, Lewy body dementia, and spongiform encephalopathy. To provide a diverse portfolio of therapeutic sm...

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Autores principales: Ramirez, Eduardo, Ganegamage, Susantha K., Elbatrawy, Ahmed A., Alnakhala, Heba, Shimanaka, Kazuma, Tripathi, Arati, Min, Sehong, Rochet, Jean-Christophe, Dettmer, Ulf, Fortin, Jessica S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249125/
https://www.ncbi.nlm.nih.gov/pubmed/37305264
http://dx.doi.org/10.1021/acsomega.3c02668

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