Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection

Bartonella henselae serologies can be nondiagnostic in immunocompromised individuals due to impaired humoral immunity. Blood polymerase chain reaction (PCR) is more useful diagnostically in immunosuppressed persons. We discuss 3 cases: 2 solid organ transplant (SOT) recipients and 1 person with huma...

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Detalles Bibliográficos
Autores principales: Kumar, Ankit, Abdulqader, Mohammed, McBride, Darrell A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249265/
https://www.ncbi.nlm.nih.gov/pubmed/37305840
http://dx.doi.org/10.1093/ofid/ofad130
Descripción
Sumario:Bartonella henselae serologies can be nondiagnostic in immunocompromised individuals due to impaired humoral immunity. Blood polymerase chain reaction (PCR) is more useful diagnostically in immunosuppressed persons. We discuss 3 cases: 2 solid organ transplant (SOT) recipients and 1 person with human immunodeficiency virus (HIV) with positive blood PCR despite negative serology.

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