Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection

Bartonella henselae serologies can be nondiagnostic in immunocompromised individuals due to impaired humoral immunity. Blood polymerase chain reaction (PCR) is more useful diagnostically in immunosuppressed persons. We discuss 3 cases: 2 solid organ transplant (SOT) recipients and 1 person with huma...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Ankit, Abdulqader, Mohammed, McBride, Darrell A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249265/
https://www.ncbi.nlm.nih.gov/pubmed/37305840
http://dx.doi.org/10.1093/ofid/ofad130
_version_ 1785055523714891776
author Kumar, Ankit
Abdulqader, Mohammed
McBride, Darrell A
author_facet Kumar, Ankit
Abdulqader, Mohammed
McBride, Darrell A
author_sort Kumar, Ankit
collection PubMed
description Bartonella henselae serologies can be nondiagnostic in immunocompromised individuals due to impaired humoral immunity. Blood polymerase chain reaction (PCR) is more useful diagnostically in immunosuppressed persons. We discuss 3 cases: 2 solid organ transplant (SOT) recipients and 1 person with human immunodeficiency virus (HIV) with positive blood PCR despite negative serology.
format Online
Article
Text
id pubmed-10249265
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-102492652023-06-09 Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection Kumar, Ankit Abdulqader, Mohammed McBride, Darrell A Open Forum Infect Dis Brief Report Bartonella henselae serologies can be nondiagnostic in immunocompromised individuals due to impaired humoral immunity. Blood polymerase chain reaction (PCR) is more useful diagnostically in immunosuppressed persons. We discuss 3 cases: 2 solid organ transplant (SOT) recipients and 1 person with human immunodeficiency virus (HIV) with positive blood PCR despite negative serology. Oxford University Press 2023-03-18 /pmc/articles/PMC10249265/ /pubmed/37305840 http://dx.doi.org/10.1093/ofid/ofad130 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Kumar, Ankit
Abdulqader, Mohammed
McBride, Darrell A
Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection
title Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection
title_full Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection
title_fullStr Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection
title_full_unstemmed Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection
title_short Utility of Polymerase Chain Reaction Versus Serology-Based Testing in Immunocompromised Patients With Bartonella henselae Infection
title_sort utility of polymerase chain reaction versus serology-based testing in immunocompromised patients with bartonella henselae infection
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249265/
https://www.ncbi.nlm.nih.gov/pubmed/37305840
http://dx.doi.org/10.1093/ofid/ofad130
work_keys_str_mv AT kumarankit utilityofpolymerasechainreactionversusserologybasedtestinginimmunocompromisedpatientswithbartonellahenselaeinfection
AT abdulqadermohammed utilityofpolymerasechainreactionversusserologybasedtestinginimmunocompromisedpatientswithbartonellahenselaeinfection
AT mcbridedarrella utilityofpolymerasechainreactionversusserologybasedtestinginimmunocompromisedpatientswithbartonellahenselaeinfection

Ejemplares similares