Significant improvement of bone marrow-derived MSC expansion from MDS patients by defined xeno-free medium

BACKGROUND: Robust and reliable in vitro and in vivo models of primary cells are necessary to study the pathomechanisms of Myelodysplastic Neoplasms (MDS) and identify novel therapeutic strategies. MDS-derived hematopoietic stem and progenitor cells (HSPCs) are reliant on the support of bone marrow...

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Detalles Bibliográficos
Autores principales: Altrock, Eva, Sens-Albert, Carla, Hofmann, Franziska, Riabov, Vladimir, Schmitt, Nanni, Xu, Qingyu, Jann, Johann-Christoph, Rapp, Felicitas, Steiner, Laurenz, Streuer, Alexander, Nowak, Verena, Obländer, Julia, Weimer, Nadine, Palme, Iris, Göl, Melda, Darwich, Ali, Wuchter, Patrick, Metzgeroth, Georgia, Jawhar, Mohamad, Hofmann, Wolf-Karsten, Nowak, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249283/
https://www.ncbi.nlm.nih.gov/pubmed/37287056
http://dx.doi.org/10.1186/s13287-023-03386-5

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