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Enhancing the Substrate Specificity of Clostridium Succinyl-CoA Reductase for Synthetic Biology and Biocatalysis

[Image: see text] Succinyl-CoA reductase (SucD) is an acylating aldehyde reductase that catalyzes the NADPH-dependent reduction of succinyl-CoA to succinic semialdehyde. The reaction sequence from succinate to crotonyl-CoA is of particular interest for several new-to-nature CO(2)-fixation pathways,...

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Detalles Bibliográficos
Autores principales:	Pfister, Pascal, Diehl, Christoph, Hammarlund, Eric, Carrillo, Martina, Erb, Tobias J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249356/ https://www.ncbi.nlm.nih.gov/pubmed/37207322 http://dx.doi.org/10.1021/acs.biochem.3c00102

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