Ravoxertinib Improves Long-Term Neurologic Deficits after Experimental Subarachnoid Hemorrhage through Early Inhibition of Erk1/2

[Image: see text] Extracellular signal-regulated kinase 1 and 2 (Erk1/2) signaling has been shown to be involved in brain injury after subarachnoid hemorrhage (SAH). A first-in-human phase I study reported that ravoxertinib hydrochloride (RAH), a novel Erk1/2 inhibitor, has an acceptable safety prof...

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Detalles Bibliográficos
Autores principales: Yang, Ming-feng, Sun, Sheng-yao, Lv, Hai-guang, Wang, Wei-qi, Li, Han-xia, Sun, Jing-yi, Zhang, Zong-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249378/
https://www.ncbi.nlm.nih.gov/pubmed/37305289
http://dx.doi.org/10.1021/acsomega.3c01296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249378/
https://www.ncbi.nlm.nih.gov/pubmed/37305289
http://dx.doi.org/10.1021/acsomega.3c01296

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