KRAS Mutation Variants and Co-occurring PI3K Pathway Alterations Impact Survival for Patients with Pancreatic Ductal Adenocarcinomas

BACKGROUND: KRAS variant alleles may have differential biological properties which impact prognosis and therapeutic options in pancreatic ductal adenocarcinomas (PDA). MATERIALS AND METHODS: We retrospectively identified patients with advanced PDA who received first-line therapy and underwent blood...

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Detalles Bibliográficos
Autores principales: Diehl, Adam C, Hannan, Lindsay M, Zhen, David B, Coveler, Andrew L, King, Gentry, Cohen, Stacey A, Harris, William P, Shankaran, Veena, Wong, Kit M, Green, Steven, Ng, Natasha, Pillarisetty, Venu G, Sham, Jonathan G, Park, James O, Reddi, Deepti, Konnick, Eric Q, Pritchard, Colin C, Baker, Kelsey, Redman, Mary, Chiorean, E Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gastrointestinal Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249424/
https://www.ncbi.nlm.nih.gov/pubmed/36124727
http://dx.doi.org/10.1093/oncolo/oyac179

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