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Activated gliosis, accumulation of amyloid β, and hyperphosphorylation of tau in aging canines with and without cognitive decline

Canine cognitive dysfunction (CCD) syndrome is a well-recognized naturally occurring disease in aged dogs, with a remarkably similar disease course, both in its clinical presentation and neuropathological changes, as humans with Alzheimer’s disease (AD). Similar to human AD patients this naturally o...

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Detalles Bibliográficos
Autores principales: Hines, Amelia D., McGrath, Stephanie, Latham, Amanda S., Kusick, Breonna, Mulligan, Lisa, Richards, McKenzie L., Moreno, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249473/
https://www.ncbi.nlm.nih.gov/pubmed/37304080
http://dx.doi.org/10.3389/fnagi.2023.1128521