Cargando…
Activated gliosis, accumulation of amyloid β, and hyperphosphorylation of tau in aging canines with and without cognitive decline
Canine cognitive dysfunction (CCD) syndrome is a well-recognized naturally occurring disease in aged dogs, with a remarkably similar disease course, both in its clinical presentation and neuropathological changes, as humans with Alzheimer’s disease (AD). Similar to human AD patients this naturally o...
Autores principales: | Hines, Amelia D., McGrath, Stephanie, Latham, Amanda S., Kusick, Breonna, Mulligan, Lisa, Richards, McKenzie L., Moreno, Julie A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249473/ https://www.ncbi.nlm.nih.gov/pubmed/37304080 http://dx.doi.org/10.3389/fnagi.2023.1128521 |
Ejemplares similares
-
Assessment of risk factors in dogs with presumptive advanced canine cognitive dysfunction
por: MacQuiddy, Brittany, et al.
Publicado: (2022) -
Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease
por: Pascoal, T A, et al.
Publicado: (2017) -
Suppression of LPS-induced tau hyperphosphorylation by serum amyloid A
por: Liu, Jin, et al.
Publicado: (2016) -
Long-term depression links amyloid-β to the pathological hyperphosphorylation of tau
por: Taylor, Henry B.C., et al.
Publicado: (2021) -
Residual reserve index modifies the effect of amyloid pathology on fluorodeoxyglucose metabolism: Implications for efficiency and capacity in cognitive reserve
por: McKenzie, Cathryn, et al.
Publicado: (2022)