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4-Methylumbelliferone enhances the effects of chemotherapy on both temozolomide-sensitive and resistant glioblastoma cells
Glioblastoma (GBM) is the most frequent malignant primary tumor of the CNS in adults, with a median survival of 14.6 months after diagnosis. The effectiveness of GBM therapies remains poor, highlighting the need for new therapeutic alternatives. In this work, we evaluated the effect of 4-methylumbel...
Autores principales: | Pibuel, Matías A., Poodts, Daniela, Sias, Sofía A., Byrne, Agustín, Hajos, Silvia E., Franco, Paula G., Lompardía, Silvina L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249561/ https://www.ncbi.nlm.nih.gov/pubmed/37291120 http://dx.doi.org/10.1038/s41598-023-35045-3 |
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