Inhibition of the JAK/STAT Pathway With Baricitinib Reduces the Multiple Organ Dysfunction Caused by Hemorrhagic Shock in Rats

The aim of this study was to investigate (a) the effects of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway inhibitor (baricitinib) on the multiple organ dysfunction syndrome (MODS) in a rat model of hemorrhagic shock (HS) and (b) whether treatment with baricit...

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Detalles Bibliográficos
Autores principales: Patel, Nikita M., Collotta, Debora, Aimaretti, Eleonora, Ferreira Alves, Gustavo, Kröller, Sarah, Coldewey, Sina M., Collino, Massimo, Thiemermann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249600/
https://www.ncbi.nlm.nih.gov/pubmed/35837955
http://dx.doi.org/10.1097/SLA.0000000000005571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249600/
https://www.ncbi.nlm.nih.gov/pubmed/35837955
http://dx.doi.org/10.1097/SLA.0000000000005571

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