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Inhibition of the JAK/STAT Pathway With Baricitinib Reduces the Multiple Organ Dysfunction Caused by Hemorrhagic Shock in Rats
The aim of this study was to investigate (a) the effects of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway inhibitor (baricitinib) on the multiple organ dysfunction syndrome (MODS) in a rat model of hemorrhagic shock (HS) and (b) whether treatment with baricit...
Autores principales: | Patel, Nikita M., Collotta, Debora, Aimaretti, Eleonora, Ferreira Alves, Gustavo, Kröller, Sarah, Coldewey, Sina M., Collino, Massimo, Thiemermann, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249600/ https://www.ncbi.nlm.nih.gov/pubmed/35837955 http://dx.doi.org/10.1097/SLA.0000000000005571 |
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