Cargando…

Ferroptosis-associated gene CISD2 suppresses colon cancer development by regulating tumor immune microenvironment

BACKGROUND: Despite the association of ferroptosis with various tumors, the specific mechanism by which it influences colon adenocarcinoma (COAD) microenvironmental equilibrium remains elusive. This study aims to elucidate how ferroptosis affects COAD microenvironmental homeostasis and its potential...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yuanyuan, Tang, Qingzhu, Ding, Ning, Zhang, Tao, Luo, Hongbiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2023
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249621/ https://www.ncbi.nlm.nih.gov/pubmed/37304867 http://dx.doi.org/10.7717/peerj.15476

Ejemplares similares

Role of ferroptosis-related genes in prognostic prediction and tumor immune microenvironment in colorectal carcinoma
por: Yang, Chao, et al.
Publicado: (2021)

Cellular heterogeneity map of diverse immune and stromal phenotypes within breast tumor microenvironment
por: Li, Yuan, et al.
Publicado: (2020)

A comprehensive analysis of immune infiltration in the tumor microenvironment of osteosarcoma
por: Yang, Hao, et al.
Publicado: (2021)

Ferroptosis-related gene signature correlates with the tumor immune features and predicts the prognosis of glioma patients
por: Hu, Yan, et al.
Publicado: (2021)

Comprehensive analysis of tumor mutation burden and immune microenvironment in gastric cancer
por: Yu, Jie, et al.
Publicado: (2021)

CISD2 Promotes Resistance to Sorafenib-Induced Ferroptosis by Regulating Autophagy in Hepatocellular Carcinoma
por: Li, Bowen, et al.
Publicado: (2021)

Identification and validation of a ferroptosis-related lncRNA signature to robustly predict the prognosis, immune microenvironment, and immunotherapy efficiency in patients with clear cell renal cell carcinoma
por: Ju, Lincheng, et al.
Publicado: (2022)

Identification of potential biomarkers associated with immune infiltration in the esophageal carcinoma tumor microenvironment
por: Wang, Zhicheng, et al.
Publicado: (2021)

CISD3 inhibition drives cystine-deprivation induced ferroptosis
por: Li, Yanchun, et al.
Publicado: (2021)

Classification of ovarian cancer associated with BRCA1 mutations, immune checkpoints, and tumor microenvironment based on immunogenomic profiling
por: Wei, Yousheng, et al.
Publicado: (2020)

Comprehensive characterization of the alternative splicing landscape in ovarian cancer reveals novel events associated with tumor-immune microenvironment
por: Sun, Dan, et al.
Publicado: (2022)

Analysis of prognostic genes in the tumor microenvironment of lung adenocarcinoma
por: Xu, Zhan-yu, et al.
Publicado: (2020)

Cellular components in tumor microenvironment of neuroblastoma and the prognostic value
por: Zhong, Xiaodan, et al.
Publicado: (2019)

The role of m6A-related genes in the prognosis and immune microenvironment of pancreatic adenocarcinoma
por: Tang, Rong, et al.
Publicado: (2020)

ENPEP as a potential predictor of immune checkpoint inhibitor efficacy
por: Wang, Aoyun, et al.
Publicado: (2021)

A ferroptosis-related gene signature for overall survival prediction and immune infiltration in lung squamous cell carcinoma
por: Miao, Ti-wei, et al.
Publicado: (2022)

Construction and validation of a 15-gene ferroptosis signature in lung adenocarcinoma
por: Tu, Guangxu, et al.
Publicado: (2021)

Integrative analysis of immune molecular subtypes and microenvironment characteristics of bladder cancer
por: Cao, Jinlong, et al.
Publicado: (2021)

Development and validation of ferroptosis-related lncRNAs signature for hepatocellular carcinoma
por: Liang, Jiaying, et al.
Publicado: (2021)

Tumor microenvironment related novel signature predict lung adenocarcinoma survival
por: Chen, Juan, et al.
Publicado: (2021)

Mining of prognosis-related genes in cervical squamous cell carcinoma immune microenvironment
por: Ma, Jiong, et al.
Publicado: (2020)

An autophagy-related prognostic signature associated with immune microenvironment features of uveal melanoma
por: Zheng, Zhuotao, et al.
Publicado: (2021)

Screening of potential key ferroptosis-related genes in sepsis
por: Cui, Shunan, et al.
Publicado: (2022)

Construction of an immune-related signature with prognostic value for colon cancer
por: Lv, Yunxia, et al.
Publicado: (2021)

Identification of prognosis-related genes in the tumor microenvironment of stomach adenocarcinoma by TCGA and GEO datasets
por: Ren, Na, et al.
Publicado: (2020)

Molecular subtypes, tumor microenvironment infiltration characterization and prognosis model based on cuproptosis in bladder cancer
por: Zhang, Heping, et al.
Publicado: (2023)

WGCNA reveals key gene modules regulated by the combined treatment of colon cancer with PHY906 and CPT11
por: Xing, Shuqin, et al.
Publicado: (2020)

Establishment of a ferroptosis-related gene signature for prognosis in lung adenocarcinoma patients
por: Cai, Jingjing, et al.
Publicado: (2021)

Development and validation of a personalized classifier to predict the prognosis and response to immunotherapy in glioma based on glycolysis and the tumor microenvironment
por: Fan, Pengfei, et al.
Publicado: (2023)

Bioinformatics identification and integrative analysis of ferroptosis-related key lncRNAs in patients with osteoarthritis
por: Yang, Tengyun, et al.
Publicado: (2023)

Identification of a ferroptosis-related gene signature (FRGS) for predicting clinical outcome in lung adenocarcinoma
por: Wang, Sheng, et al.
Publicado: (2021)

The landscape of tumors-infiltrate immune cells in papillary thyroid carcinoma and its prognostic value
por: Huang, Yanyi, et al.
Publicado: (2021)

Identification of colon tumor marker NKD1 via integrated bioinformatics analysis and experimental validation
por: Wang, Yue, et al.
Publicado: (2021)

Construction of a prognostic model for non-small-cell lung cancer based on ferroptosis-related genes
por: Han, Ke, et al.
Publicado: (2021)

Copy number variation analysis of m(6)A regulators identified METTL3 as a prognostic and immune‐related biomarker in bladder cancer
por: Wang, Xiaoshuai, et al.
Publicado: (2021)

miR-6315 silencing protects against spinal cord injury through the Smo and anti-ferroptosis pathway
por: Ma, Zheng, et al.
Publicado: (2023)

Comprehensive genomic analysis of microenvironment phenotypes in ovarian cancer
por: Wang, Jingshu, et al.
Publicado: (2020)

Metabolic regulation of ferroptosis in the tumor microenvironment
por: Mbah, Nneka E., et al.
Publicado: (2022)

Pan‐cancer analyses reveal that increased Hedgehog activity correlates with tumor immunosuppression and resistance to immune checkpoint inhibitors
por: Jiang, Junjie, et al.
Publicado: (2021)

The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi‐omics study
por: Xu, Fangshi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_r6avg95gpuvls3g9502bo8s4bm