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Biotransformation novel advances – 2021 year in review*
Biotransformation field is constantly evolving with new molecular structures and discoveries of metabolic pathways that impact efficacy and safety. Recent review by Kramlinger et al. (2022) nicely captures the future (and the past) of highly impactful science of biotransformation (see the first arti...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249656/ https://www.ncbi.nlm.nih.gov/pubmed/35815654 http://dx.doi.org/10.1080/03602532.2022.2097253 |
| _version_ | 1785055604621967360 |
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| author | Khojasteh, S. Cyrus Argikar, Upendra A. Cho, Sungjoon Crouch, Rachel Heck, Carley J. S. Johnson, Kevin M. Kalgutkar, Amit S. King, Lloyd Maw, Hlaing (Holly) Seneviratne, Herana Kamal Wang, Shuai Wei, Cong Zhang, Donglu Jackson, Klarissa D. |
| author_facet | Khojasteh, S. Cyrus Argikar, Upendra A. Cho, Sungjoon Crouch, Rachel Heck, Carley J. S. Johnson, Kevin M. Kalgutkar, Amit S. King, Lloyd Maw, Hlaing (Holly) Seneviratne, Herana Kamal Wang, Shuai Wei, Cong Zhang, Donglu Jackson, Klarissa D. |
| author_sort | Khojasteh, S. Cyrus |
| collection | PubMed |
| description | Biotransformation field is constantly evolving with new molecular structures and discoveries of metabolic pathways that impact efficacy and safety. Recent review by Kramlinger et al. (2022) nicely captures the future (and the past) of highly impactful science of biotransformation (see the first article). Based on the selected articles, this review was categorized into three sections: (1) new modalities biotransformation, (2) drug discovery biotransformation, and (3) drug development biotransformation (Table 1). |
| format | Online Article Text |
| id | pubmed-10249656 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-102496562023-06-08 Biotransformation novel advances – 2021 year in review* Khojasteh, S. Cyrus Argikar, Upendra A. Cho, Sungjoon Crouch, Rachel Heck, Carley J. S. Johnson, Kevin M. Kalgutkar, Amit S. King, Lloyd Maw, Hlaing (Holly) Seneviratne, Herana Kamal Wang, Shuai Wei, Cong Zhang, Donglu Jackson, Klarissa D. Drug Metab Rev Article Biotransformation field is constantly evolving with new molecular structures and discoveries of metabolic pathways that impact efficacy and safety. Recent review by Kramlinger et al. (2022) nicely captures the future (and the past) of highly impactful science of biotransformation (see the first article). Based on the selected articles, this review was categorized into three sections: (1) new modalities biotransformation, (2) drug discovery biotransformation, and (3) drug development biotransformation (Table 1). 2022-08 2022-08-30 /pmc/articles/PMC10249656/ /pubmed/35815654 http://dx.doi.org/10.1080/03602532.2022.2097253 Text en Full Terms & Conditions of access and use can be found at https://www.tandfonline.com/action/journalInformation?journalCode=idmr20 https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. |
| spellingShingle | Article Khojasteh, S. Cyrus Argikar, Upendra A. Cho, Sungjoon Crouch, Rachel Heck, Carley J. S. Johnson, Kevin M. Kalgutkar, Amit S. King, Lloyd Maw, Hlaing (Holly) Seneviratne, Herana Kamal Wang, Shuai Wei, Cong Zhang, Donglu Jackson, Klarissa D. Biotransformation novel advances – 2021 year in review* |
| title | Biotransformation novel advances – 2021 year in review* |
| title_full | Biotransformation novel advances – 2021 year in review* |
| title_fullStr | Biotransformation novel advances – 2021 year in review* |
| title_full_unstemmed | Biotransformation novel advances – 2021 year in review* |
| title_short | Biotransformation novel advances – 2021 year in review* |
| title_sort | biotransformation novel advances – 2021 year in review* |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249656/ https://www.ncbi.nlm.nih.gov/pubmed/35815654 http://dx.doi.org/10.1080/03602532.2022.2097253 |
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