A Rare Cause of Abdominal Pain: Erdheim-Chester Disease

A 65-year-old man presented with hematuria, night sweats, nausea, intermittent nonbloody diarrhea, and abdominal pain. Computed tomography angiogram with enterography showed retroperitoneal fibrosis surrounding both kidneys and ureters without any evidence of vascular obstruction or hydronephrosis....

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Autores principales: Chatterjee, Arjun, de la Fuente, Jaime, Rech, Karen L., Takahashi, Naoki, Majumder, Shounak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249710/
https://www.ncbi.nlm.nih.gov/pubmed/37305802
http://dx.doi.org/10.14309/crj.0000000000001049
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author Chatterjee, Arjun
de la Fuente, Jaime
Rech, Karen L.
Takahashi, Naoki
Majumder, Shounak
author_facet Chatterjee, Arjun
de la Fuente, Jaime
Rech, Karen L.
Takahashi, Naoki
Majumder, Shounak
author_sort Chatterjee, Arjun
collection PubMed
description A 65-year-old man presented with hematuria, night sweats, nausea, intermittent nonbloody diarrhea, and abdominal pain. Computed tomography angiogram with enterography showed retroperitoneal fibrosis surrounding both kidneys and ureters without any evidence of vascular obstruction or hydronephrosis. Laparoscopic biopsy demonstrated fibroadipose tissue involved by a subtle histiocytic infiltrate in a background of marked fibrosis, scattered lymphocytes, and plasma cells. The histiocytes strongly expressed CD163, Factor XIIIa, and BRAF V600E. He was diagnosed with Erdheim-Chester disease, a rare histiocytic neoplasm uncommonly presenting with gastroenterological manifestations.
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spelling pubmed-102497102023-06-09 A Rare Cause of Abdominal Pain: Erdheim-Chester Disease Chatterjee, Arjun de la Fuente, Jaime Rech, Karen L. Takahashi, Naoki Majumder, Shounak ACG Case Rep J Case Report A 65-year-old man presented with hematuria, night sweats, nausea, intermittent nonbloody diarrhea, and abdominal pain. Computed tomography angiogram with enterography showed retroperitoneal fibrosis surrounding both kidneys and ureters without any evidence of vascular obstruction or hydronephrosis. Laparoscopic biopsy demonstrated fibroadipose tissue involved by a subtle histiocytic infiltrate in a background of marked fibrosis, scattered lymphocytes, and plasma cells. The histiocytes strongly expressed CD163, Factor XIIIa, and BRAF V600E. He was diagnosed with Erdheim-Chester disease, a rare histiocytic neoplasm uncommonly presenting with gastroenterological manifestations. Wolters Kluwer 2023-06-08 /pmc/articles/PMC10249710/ /pubmed/37305802 http://dx.doi.org/10.14309/crj.0000000000001049 Text en © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Chatterjee, Arjun
de la Fuente, Jaime
Rech, Karen L.
Takahashi, Naoki
Majumder, Shounak
A Rare Cause of Abdominal Pain: Erdheim-Chester Disease
title A Rare Cause of Abdominal Pain: Erdheim-Chester Disease
title_full A Rare Cause of Abdominal Pain: Erdheim-Chester Disease
title_fullStr A Rare Cause of Abdominal Pain: Erdheim-Chester Disease
title_full_unstemmed A Rare Cause of Abdominal Pain: Erdheim-Chester Disease
title_short A Rare Cause of Abdominal Pain: Erdheim-Chester Disease
title_sort rare cause of abdominal pain: erdheim-chester disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249710/
https://www.ncbi.nlm.nih.gov/pubmed/37305802
http://dx.doi.org/10.14309/crj.0000000000001049
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