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Inclusion of a GaAs detector model in the Photon Counting Toolkit software for the study of breast imaging systems

We present an upgraded version of the Photon Counting Toolkit (PcTK), a freely available by request MATLAB tool for the simulation of semiconductor-based photon counting detectors (PCD), which has been extended and validated to account for gallium arsenide (GaAs)-based PCD(s). The modified PcTK vers...

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Autores principales: Ghammraoui, Bahaa, Taguchi, Katsuyuki, Glick, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249813/
https://www.ncbi.nlm.nih.gov/pubmed/37289737
http://dx.doi.org/10.1371/journal.pone.0270387
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author Ghammraoui, Bahaa
Taguchi, Katsuyuki
Glick, Stephen J.
author_facet Ghammraoui, Bahaa
Taguchi, Katsuyuki
Glick, Stephen J.
author_sort Ghammraoui, Bahaa
collection PubMed
description We present an upgraded version of the Photon Counting Toolkit (PcTK), a freely available by request MATLAB tool for the simulation of semiconductor-based photon counting detectors (PCD), which has been extended and validated to account for gallium arsenide (GaAs)-based PCD(s). The modified PcTK version was validated by performing simulations and acquiring experimental data for three different cases. The LAMBDA 60 K module planar detector (X-Spectrum GmbH, Germany) based on the Medipix3 ASIC technology was used in all cases. This detector has a 500-μm thick GaAs sensor and a 256 × 256-pixel array with 55 μm pixel size. The first validation was a comparison between simulated and measured spectra from a (109)Cd radionuclide source. In the second validation study, experimental measurements and simulations of mammography spectra were generated to observe the performance of the GaAs version of the PcTK with polychromatic radiation used in conventional x-ray imaging systems. The third validation study used single event analysis to validate the spatio-energetic model of the extended PcTK version. Overall, the software provided a good agreement between simulated and experimental data, validating the accuracy of the GaAs model. The software could be an attractive tool for accurate simulation of breast imaging modalities relying on photon counting detectors and therefore could assist in their characterization and optimization.
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spelling pubmed-102498132023-06-09 Inclusion of a GaAs detector model in the Photon Counting Toolkit software for the study of breast imaging systems Ghammraoui, Bahaa Taguchi, Katsuyuki Glick, Stephen J. PLoS One Research Article We present an upgraded version of the Photon Counting Toolkit (PcTK), a freely available by request MATLAB tool for the simulation of semiconductor-based photon counting detectors (PCD), which has been extended and validated to account for gallium arsenide (GaAs)-based PCD(s). The modified PcTK version was validated by performing simulations and acquiring experimental data for three different cases. The LAMBDA 60 K module planar detector (X-Spectrum GmbH, Germany) based on the Medipix3 ASIC technology was used in all cases. This detector has a 500-μm thick GaAs sensor and a 256 × 256-pixel array with 55 μm pixel size. The first validation was a comparison between simulated and measured spectra from a (109)Cd radionuclide source. In the second validation study, experimental measurements and simulations of mammography spectra were generated to observe the performance of the GaAs version of the PcTK with polychromatic radiation used in conventional x-ray imaging systems. The third validation study used single event analysis to validate the spatio-energetic model of the extended PcTK version. Overall, the software provided a good agreement between simulated and experimental data, validating the accuracy of the GaAs model. The software could be an attractive tool for accurate simulation of breast imaging modalities relying on photon counting detectors and therefore could assist in their characterization and optimization. Public Library of Science 2023-06-08 /pmc/articles/PMC10249813/ /pubmed/37289737 http://dx.doi.org/10.1371/journal.pone.0270387 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Ghammraoui, Bahaa
Taguchi, Katsuyuki
Glick, Stephen J.
Inclusion of a GaAs detector model in the Photon Counting Toolkit software for the study of breast imaging systems
title Inclusion of a GaAs detector model in the Photon Counting Toolkit software for the study of breast imaging systems
title_full Inclusion of a GaAs detector model in the Photon Counting Toolkit software for the study of breast imaging systems
title_fullStr Inclusion of a GaAs detector model in the Photon Counting Toolkit software for the study of breast imaging systems
title_full_unstemmed Inclusion of a GaAs detector model in the Photon Counting Toolkit software for the study of breast imaging systems
title_short Inclusion of a GaAs detector model in the Photon Counting Toolkit software for the study of breast imaging systems
title_sort inclusion of a gaas detector model in the photon counting toolkit software for the study of breast imaging systems
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249813/
https://www.ncbi.nlm.nih.gov/pubmed/37289737
http://dx.doi.org/10.1371/journal.pone.0270387
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