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Allergic Bronchopulmonary Aspergillosis: A Case Report

Allergic bronchopulmonary aspergillosis (ABPA) is an underdiagnosed lung condition in patients with asthma and cystic fibrosis. Its clinical and diagnostic manifestations result from an allergic response to multiple antigens expressed by Aspergillus fumigatus, which colonize the bronchial mucus. Thi...

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Autores principales: Bouali, Siham, Legssyer, Imane, Thouil, Afaf, Kouismi, Hatim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250130/
https://www.ncbi.nlm.nih.gov/pubmed/37303384
http://dx.doi.org/10.7759/cureus.38778
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author Bouali, Siham
Legssyer, Imane
Thouil, Afaf
Kouismi, Hatim
author_facet Bouali, Siham
Legssyer, Imane
Thouil, Afaf
Kouismi, Hatim
author_sort Bouali, Siham
collection PubMed
description Allergic bronchopulmonary aspergillosis (ABPA) is an underdiagnosed lung condition in patients with asthma and cystic fibrosis. Its clinical and diagnostic manifestations result from an allergic response to multiple antigens expressed by Aspergillus fumigatus, which colonize the bronchial mucus. This report presents the case of a 73-year-old female patient referred to our hospital for uncontrolled asthma for 35 years. The diagnosis of ABPA was made on the basis of clinical symptoms, peripheral blood eosinophilia, elevated total serum immunoglobulin E, positive aspergillus serology, and bronchiectasis with mucoid impaction. Systemic corticosteroids and antifungal therapy came up with satisfactory clinical results.
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spelling pubmed-102501302023-06-10 Allergic Bronchopulmonary Aspergillosis: A Case Report Bouali, Siham Legssyer, Imane Thouil, Afaf Kouismi, Hatim Cureus Allergy/Immunology Allergic bronchopulmonary aspergillosis (ABPA) is an underdiagnosed lung condition in patients with asthma and cystic fibrosis. Its clinical and diagnostic manifestations result from an allergic response to multiple antigens expressed by Aspergillus fumigatus, which colonize the bronchial mucus. This report presents the case of a 73-year-old female patient referred to our hospital for uncontrolled asthma for 35 years. The diagnosis of ABPA was made on the basis of clinical symptoms, peripheral blood eosinophilia, elevated total serum immunoglobulin E, positive aspergillus serology, and bronchiectasis with mucoid impaction. Systemic corticosteroids and antifungal therapy came up with satisfactory clinical results. Cureus 2023-05-09 /pmc/articles/PMC10250130/ /pubmed/37303384 http://dx.doi.org/10.7759/cureus.38778 Text en Copyright © 2023, Bouali et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Allergy/Immunology
Bouali, Siham
Legssyer, Imane
Thouil, Afaf
Kouismi, Hatim
Allergic Bronchopulmonary Aspergillosis: A Case Report
title Allergic Bronchopulmonary Aspergillosis: A Case Report
title_full Allergic Bronchopulmonary Aspergillosis: A Case Report
title_fullStr Allergic Bronchopulmonary Aspergillosis: A Case Report
title_full_unstemmed Allergic Bronchopulmonary Aspergillosis: A Case Report
title_short Allergic Bronchopulmonary Aspergillosis: A Case Report
title_sort allergic bronchopulmonary aspergillosis: a case report
topic Allergy/Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250130/
https://www.ncbi.nlm.nih.gov/pubmed/37303384
http://dx.doi.org/10.7759/cureus.38778
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