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Allergic Bronchopulmonary Aspergillosis: A Case Report
Allergic bronchopulmonary aspergillosis (ABPA) is an underdiagnosed lung condition in patients with asthma and cystic fibrosis. Its clinical and diagnostic manifestations result from an allergic response to multiple antigens expressed by Aspergillus fumigatus, which colonize the bronchial mucus. Thi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250130/ https://www.ncbi.nlm.nih.gov/pubmed/37303384 http://dx.doi.org/10.7759/cureus.38778 |
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author | Bouali, Siham Legssyer, Imane Thouil, Afaf Kouismi, Hatim |
author_facet | Bouali, Siham Legssyer, Imane Thouil, Afaf Kouismi, Hatim |
author_sort | Bouali, Siham |
collection | PubMed |
description | Allergic bronchopulmonary aspergillosis (ABPA) is an underdiagnosed lung condition in patients with asthma and cystic fibrosis. Its clinical and diagnostic manifestations result from an allergic response to multiple antigens expressed by Aspergillus fumigatus, which colonize the bronchial mucus. This report presents the case of a 73-year-old female patient referred to our hospital for uncontrolled asthma for 35 years. The diagnosis of ABPA was made on the basis of clinical symptoms, peripheral blood eosinophilia, elevated total serum immunoglobulin E, positive aspergillus serology, and bronchiectasis with mucoid impaction. Systemic corticosteroids and antifungal therapy came up with satisfactory clinical results. |
format | Online Article Text |
id | pubmed-10250130 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-102501302023-06-10 Allergic Bronchopulmonary Aspergillosis: A Case Report Bouali, Siham Legssyer, Imane Thouil, Afaf Kouismi, Hatim Cureus Allergy/Immunology Allergic bronchopulmonary aspergillosis (ABPA) is an underdiagnosed lung condition in patients with asthma and cystic fibrosis. Its clinical and diagnostic manifestations result from an allergic response to multiple antigens expressed by Aspergillus fumigatus, which colonize the bronchial mucus. This report presents the case of a 73-year-old female patient referred to our hospital for uncontrolled asthma for 35 years. The diagnosis of ABPA was made on the basis of clinical symptoms, peripheral blood eosinophilia, elevated total serum immunoglobulin E, positive aspergillus serology, and bronchiectasis with mucoid impaction. Systemic corticosteroids and antifungal therapy came up with satisfactory clinical results. Cureus 2023-05-09 /pmc/articles/PMC10250130/ /pubmed/37303384 http://dx.doi.org/10.7759/cureus.38778 Text en Copyright © 2023, Bouali et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Allergy/Immunology Bouali, Siham Legssyer, Imane Thouil, Afaf Kouismi, Hatim Allergic Bronchopulmonary Aspergillosis: A Case Report |
title | Allergic Bronchopulmonary Aspergillosis: A Case Report |
title_full | Allergic Bronchopulmonary Aspergillosis: A Case Report |
title_fullStr | Allergic Bronchopulmonary Aspergillosis: A Case Report |
title_full_unstemmed | Allergic Bronchopulmonary Aspergillosis: A Case Report |
title_short | Allergic Bronchopulmonary Aspergillosis: A Case Report |
title_sort | allergic bronchopulmonary aspergillosis: a case report |
topic | Allergy/Immunology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10250130/ https://www.ncbi.nlm.nih.gov/pubmed/37303384 http://dx.doi.org/10.7759/cureus.38778 |
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